Hence laughably wrong (sorry, bit of an inside joke). First, matter and energy must be conserved, which means (counterintuitively) that it must be possible for both matter and energy to be completely destroyed (and created). Imagine an electron hitting or "scattering" off of a proton or something. Using matrix mechanics or, better still the wave equation, we run into a problem: the electron will remain an electron (whatever that is). However, the incredibly high energy fluctuations in quantum physics run into problems here with special relativity. Thus, in relativistic quantum physics like QED or quantum field theory in general, this problem must be dealt with and was (over many decades of brilliant work that came to be the standard model of particle physics). The example situation (can) create
ex nihilo an electron and a positron. The mathematical (and then experimental) discovery of the positron was the beginning of antimatter physics, as the positron is the "anti-electron". Which means that they same electron that produces a new electron/positron pair has created one "particle" that can destroy the other.
It gets worse. I'll skip over "virtual particles" as this would have to get into why all particles are basically virtual and virtual particles aren't really virtual. We can keep it simple by simply noting that the vast majority of particles don't live for more than an instant. This is generally referred to as decay, and sometimes it is decay in the sense one would expect: simply a breakdown of matter into smaller pieces or something. Often, it means the complete disappearance of the particle. Every particle (and there are so many that most don't have names, just symbols/letters like Z or τ+) also has an antiparticle. The antiparticles has the same lifetime as its corresponding particle.
The organization responsible for providing updates on the state of particle physics to the scientific community is the Particle Data Group. The last paper I read from them, "Review of Particle Physics" (
Phys. Rev. D 86, 010001) was a bit longer than your average science paper: 1500+ pages. We keep finding new particles created and annihilated.
As in, everything about it utterly gone?
What was there to begin with? In quantum mechanics, systems aren't "physical" in that e.g., the state of any system is a mathematical state in a mathematical state that changes by applying mathematical functions we call observables despite the fact that they can't be observed (they're mathematical functions, after all). The relationship between physical systems and the systems described by QM is unknown. Particle physics is QM-plus: Instead of merely having observables like position, time, momentum (which is position and mass), spin, etc., as operators (mathematical functions that act on a mathematical system), we have to scrap wavefunctions (and matrix mechanics) and treat then as fields which are operators we parametrize by space and time variables (some observables are still operators, but as operators are no longer the same mathematical functions as they were in QM, this doesn't help).
Not spread out over vast distances, but literally gone?
Literally gone. Physically, we aren't sure what was there to begin with but we do know that anything material (as in made of matter) that may have existed is completely gone.