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Covid and the vaccine. The studies

We Never Know

No Slack
This is my opinion. You don't have to agree or disagree because its my opinion and isn't up for debate.

Unless the study tells me the age, sex, health status/history, etc about its participants then that study doesn't mean much to me.

I can do a study of 3000 participants and say the evidence shows without the vaccine 60% died. But if 63% were older and in questionable health they probably would have died anyway.

Or

I can do a study with 3000 participants
and say the evidence shows with the vaccine only 20% got severe. But if 83% were young to middle aged and in good to fair health they probably wouldn't have gotten severe anyway.

What I'm saying is with all the studies I've read they really don't tell us much about the participants which in reality makes a huge difference.

That's my opinion.
 
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SomeRandom

Still learning to be wise
Staff member
Premium Member
Well fair enough
Though I have to wonder, would you say the same about cancer?
There are probably thousands of cancer studies detailing the treatments, death rates with and without treatments and how effective they are depending on the type. But might not show you mitigating factors, such as age (young people probably have a higher chance of remission, after all.)
Other health issues, failed experimental treatments etc

Sure data can be very easily manipulated. But science isn’t some conspiracy theory cabal. If the worlds leading doctors say, hey, this polio vaccine reduces the risk of polio, would you still say the same thing about those studies?
Just curious
 

We Never Know

No Slack
Well fair enough
Though I have to wonder, would you say the same about cancer?
There are probably thousands of cancer studies detailing the treatments, death rates with and without treatments and how effective they are depending on the type. But might not show you mitigating factors, such as age (young people probably have a higher chance of remission, after all.)
Other health issues, failed experimental treatments etc

Sure data can be very easily manipulated. But science isn’t some conspiracy theory cabal. If the worlds leading doctors say, hey, this polio vaccine reduces the risk of polio, would you still say the same thing about those studies?
Just curious

Who said science is a conspiracy theory?

Yes I would say the same. Age, health(current and history), lifestyle, diet, weight, how active, etc all have an impact on the study in my opinion.

In my opinion there won't be a cure for cancer anytime soon. Cancer is a business. It generates lots of revenue and many people depend on treating it for a job. If we cured cancer billions in revenue would be lost along with millions of jobs.

Edit....
Its kind of like wars. Without them billions of revenue and millions of jobs would be lost.
 

SomeRandom

Still learning to be wise
Staff member
Premium Member
Who said science is a conspiracy theory?

Yes I would say the same. Age, health(current and history), lifestyle, diet, weight, how active, etc all have an impact on the study in my opinion.

In my opinion there won't be a cure for cancer anytime soon. Cancer is a business. It generates lots of revenue and many people depend on treating it for a job. If we cured cancer billions in revenue would be lost along with millions of jobs.

Edit....
Its kind of like wars. Without them billions of revenue and millions of jobs would be lost.
Hmm. Whilst I can somewhat agree with that viewpoint. A part of me still reacts with a bit of shock. Cancer is technically cured routinely. Many forms of cancer respond very well to radiation and chemotherapy. Granted I think there’s probably a better way out there somewhere in the future. Maybe. Hopefully. But cures cutting into profits assumes the US medical model is the whole world. It’s not. If someone cured all forms of cancer, it would just be paid for by the taxes in most countries. The company may even hold it ransom in America. Then again, maybe that’s just a bit too optimistic of me. Since no one I know pays for life saving treatment where I live. Not like Americans seem to.

Also and this is irrelevant I just thought this was amusing, having tried to find info on the profits of COVID vaccines I have since discovered that BioNTech, the company behind Pfizer was actually working on a skin cancer vaccine before COVID
 
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We Never Know

No Slack
Hmm. Whilst I can somewhat agree with that viewpoint. A part of me still reacts with a bit of shock. Cancer is technically cured routinely. Many forms of cancer respond very well to radiation and chemotherapy. Granted I think there’s probably a better way out there somewhere in the future. Maybe. Hopefully. But cures cutting into profits assumes the US medical model is the whole world. It’s not. If someone cured all forms of cancer, it would just be paid for by the taxes in most countries. The company may even hold it ransom in America. Then again, maybe that’s just a bit too optimistic of me. Since my father got life saving treatment daily without paying a single dime. So I come from a different mindset of medicine, if you get my drift?

Cancer treatment depend on how much money you have. The more money you have, the better treatment you get. Not everyone can get treatment in say, Cancer Treatment Centers of America, Johns Hopkins, or the Mayo Clinic.
Regardless even the weatlthiest will die from cancer after spending millions.
 

We Never Know

No Slack
Hmm. Whilst I can somewhat agree with that viewpoint. A part of me still reacts with a bit of shock. Cancer is technically cured routinely. Many forms of cancer respond very well to radiation and chemotherapy. Granted I think there’s probably a better way out there somewhere in the future. Maybe. Hopefully. But cures cutting into profits assumes the US medical model is the whole world. It’s not. If someone cured all forms of cancer, it would just be paid for by the taxes in most countries. The company may even hold it ransom in America. Then again, maybe that’s just a bit too optimistic of me. Since no one I know pays for life saving treatment where I live. Not like Americans seem to.

Also and this is irrelevant I just thought this was amusing, having tried to find info on the profits of COVID vaccines I have since discovered that BioNTech, the company behind Pfizer was actually working on a skin cancer vaccine before COVID

Hope your father got better. There are some places if a person meets criteria or same others that don't bill patients. Its paid for by donors, supporters and the government. .
I dont mean to sound bad but someone pays for it. Those Dr and staff get paid good money somehow.
 

SomeRandom

Still learning to be wise
Staff member
Premium Member
Cancer treatment depend on how much money you have. The more money you have, the better treatment you get. Not everyone can get treatment in say, Cancer Treatment Centers of America, Johns Hopkins, or the Mayo Clinic.
Regardless even the weatlthiest will die from cancer after spending millions.
Yikes!
My father was on pension (I don’t know if there’s a US equivalent. Umm like a retirement funded by your Superannuation, if you guys have that?)
So he was very low income. Still got all the best cancer treatment. Well okay, the public hospital scene is pretty crummy, but it’s basically the same treatments as private is what I mean by that.
Here wealth only comes into play if you want to skip the queue or your condition is very rare and you want something experimental. Not to say the rich don’t have all sorts of luxuries the rest of us don’t, they absolutely do. But as a taxpayer I only chip in extra if I want some bells and whistles to my hospital stay.
 

We Never Know

No Slack
Yikes!
My father was on pension (I don’t know if there’s a US equivalent. Umm like a retirement funded by your Superannuation, if you guys have that?)
So he was very low income. Still got all the best cancer treatment. Well okay, the public hospital scene is pretty crummy, but it’s basically the same treatments as private is what I mean by that.
Here wealth only comes into play if you want to skip the queue or your condition is very rare and you want something experimental. Not to say the rich don’t have all sorts of luxuries the rest of us don’t, they absolutely do. But as a taxpayer I only chip in extra if I want some bells and whistles to my hospital stay.
I think a lot of it has to do with insurance.
Insurance companies are like casino's, they pay out some but they are there to make money.
 

SomeRandom

Still learning to be wise
Staff member
Premium Member
Hope your father got better. There are some places if a person meets criteria or same others that don't bill patients. Its paid for by donors, supporters and the government. .
I dont mean to sound bad but someone pays for it. Those Dr and staff get paid good money somehow.
Unfortunately he wasn’t lucky. But death is a part of life. But thank you
I get what you mean. I guess since my tax dollars goes towards our Medicare (public health care system) I see doctors more like one would see a civil servant I might want there to be a bit more government support, and I think they deserve a very good wage for their work and skills, but I more or less pay their wages.
 
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SomeRandom

Still learning to be wise
Staff member
Premium Member
I think a lot of it has to do with insurance.
Insurance companies are like casino's, they pay out some but they are there to make money.
The more I hear about American health care insurers the less I think of them, to be completely honest. They sound like such opportunistic scum.
 

lewisnotmiller

Grand Hat
Staff member
Premium Member
This is my opinion. You don't have to agree or disagree because its my opinion and isn't up for debate.

Unless the study tells me the age, sex, health status/history, etc about its participants then that study doesn't mean much to me.

I can do a study of 3000 participants and say the evidence shows without the vaccine 60% died. But if 63% were older and in questionable health they probably would have died anyway.

Or

I can do a study with 3000 participants
and say the evidence shows with the vaccine only 20% got severe. But if 83% were young to middle aged and in good to fair health they probably wouldn't have gotten severe anyway.

What I'm saying is with all the studies I've read they really don't tell us much about the participants which in reality makes a huge difference.

That's my opinion.

Are you suggesting you've read a bunch of studies and none of them had control groups?
 

Jayhawker Soule

-- untitled --
Premium Member
What I'm saying is with all the studies I've read they really don't tell us much about the participants which in reality makes a huge difference.
And yet it makes a huge difference to credible experts in the field, i.e., to those actually capable of evaluating the statistics. That you deem yourself to be competent to counterpose your "analysis" to that of the medical community strikes me as more than a little incredible.

That's my opinion.
Not all opinions are created equal. Again, some are ignorant to the point of being malignant.

But, since you seem so intent on sharing your opinion, perhaps you'll allow me to share mine: the more uninformed people who think like you, the more innocent people will die.
 

It Aint Necessarily So

Veteran Member
Premium Member
This is my opinion. You don't have to agree or disagree because its my opinion and isn't up for debate. Unless the study tells me the age, sex, health status/history, etc about its participants then that study doesn't mean much to me. I can do a study of 3000 participants and say the evidence shows without the vaccine 60% died. But if 63% were older and in questionable health they probably would have died anyway.

Or

I can do a study with 3000 participants and say the evidence shows with the vaccine only 20% got severe. But if 83% were young to middle aged and in good to fair health they probably wouldn't have gotten severe anyway. What I'm saying is with all the studies I've read they really don't tell us much about the participants which in reality makes a huge difference. That's my opinion.

Would you be able to evaluate the study if you saw the data you mentioned? It's a learned skill. If you can and want to do so, you generally need to find the original study published in a reputable journal, where such data is provided

Your choices are these:

[1] Look at the original published study. Go to the methods section of the abstract, and look at how the study was designed. Was it randomized, and controlled. Was it sufficiently powered (enough people studied) to achieve statistical significance? You'll need to know how to evaluate such data to do that, but you can come to your own conclusions and compare them to the study's conclusions. If available, you can review criticisms of the study if any (peer review).

[2] If you can't or don't want to do that, the next best thing is to identify trustworthy sources. If you know how to do that, and have accurately identified the experts, you can trust them provisionally. This is different from the genetic error, which judges the correctness of the conclusion of an argument by its source. You know that the conclusion may be flawed, but you also know that your expert's opinion is more reliable than your own, and if you are a good judge of who is trustworthy (even if not always correct), it is rational to decide that the experts are probably correct, as when you consult an attorney or physician. The genetic error says something like, "My doctor has the correct diagnosis because he's a good doctor" rather than, "My doctor is more likely correct than I am, and I will defer my judgment to the expert."

[3] Do neither of these things and just ignore the study, or accept or reject it on faith.

Let's look at a study at Effects of intercessory prayer on patients with rheumatoid arthritis - PubMed :

Effects of intercessory prayer on patients with rheumatoid arthritis

D A Matthews 1, S M Marlowe, F S MacNutt
South Med J . 2000 Dec;93(12):1177-86.

Abstract

Background: Many individuals pray during times of illness, but the clinical effects of prayer are not well-understood.

Methods: We prospectively studied a cohort of 40 patients (mean age, 62 years; 100% white; 82% women) at a private rheumatology practice. All had class II or III rheumatoid arthritis and took stable doses of antirheumatic medications. All received a 3-day intervention, including 6 hours of education and 6 hours of direct-contact intercessory prayer. Nineteen randomly selected sample patients had 6 months of daily, supplemental intercessory prayer by individuals located elsewhere. Ten arthritis-specific outcome variables were measured at baseline and at 3-month intervals for 1 year.

Results: Patients receiving in-person intercessory prayer showed significant overall improvement during 1-year follow-up. No additional effects from supplemental, distant intercessory prayer were found.

Conclusions: In-person intercessory prayer may be a useful adjunct to standard medical care for certain patients with rheumatoid arthritis. Supplemental, distant intercessory prayer offers no additional benefits.​

There's your data in the methods section. Forty people were studied. Their average age was 62, all white, 82% female. All had training and one-on-one direct prayer sessions for a total of six hours, but about half also had prayer from a distance. The abstract doesn't tell us if the patients knew this. Specific disease markers not named were measured four times over a year.

What do you think? Do these data support the conclusion? As I suggested, one ought to have some familiarity with doing this before saying, "Show me the data." Here's my assessment:

There is no control group for direct prayer. It is probably assumed that patients not in the study would be expected to be the same in six months, but maybe modern treatments make improvement over six months common anyway. Is forty people enough to reveal a difference between prayer and no prayer if you did include a control group? Statisticians generally provide those answers, which are generally included in the abstract, but not this time.

Although the study had no control group, those in the study were divided about evenly into those who received direct and remote prayer, and those that received only direct prayer. Is that enough people to conclude that the lack of effect of remote prayer was due to there being no effect? Perhaps if the study had been 2000 people, the groups would have begun to separate.

Look at how weak the conclusion is. Prayer might be useful. Wasn't that assumed before going into the study? If that weren't already believed to be possible, why do the study? Can we be sure that the second sentence in the conclusion is correct? I'd have preferred that it be worded that the remote prayer didn't lead to a detectable difference, not that it offers no benefit.

And what about the Southern Medical Journal? I'm a retired physician, and never heard of it, but that doesn't mean that it isn't reputable. I didn't find much on it, but it looks a little suspect to me. The Southern Medical Association publishes it, a professional organization said to be dedicated to educating clinical physicians

Judge for yourself: Southern Medical Journal - Wikipedia and Southern Medical Association (SMA)

I'll defer to the scientists present on RF who have actually been involved in published studies to tell you more if there is more to be said (I only read them), but I concluded that this study has no value and reveals nothing. Notice that this is me visiting the first category above, but putting myself into the second anyway, since there are several posters here on RF whose judgment I would defer to if they told me I had it wrong, but were unable to explain why in a way that I was prepared to understand.

Given your comments, I'd ask myself if I were really looking for scientific guidance or not. I hear so many people that I believe are simply more afraid of the vaccine than the virus that they just don't want it, but don't feel like that's an adequate answer. So, they give reasons to justify the choice, as if those reasons were what led the to dispassionately and rationally conclude that they should wait on the vaccine. They say they are waiting for more information, when there is enough information now to decide in favor of being vaccinated. Sure, there's a long shot possibility that in the end, more people will have died from an as yet unknown complication of the vaccine in five or twenty years than from the virus, but that is not a reason to choose to risk the virus unvaccinated instead.

Remarkably, nobody I know has died from COVID yet, but just now, there is one about to. He's an acquaintance named Howard, a retired attorney and expat living in Mexico like I do who I was in a play with a few years back. He's an eccentric and impulsive guy, on his fifth or sixth wife, third in the eight years I've known him. He didn't want the vaccine. He was waiting for more information, he said. He wanted to see how others did with the vaccine first. We were his guinea pigs, he thought, not realizing that he was in the "study" as well as part of the control group, the unvaccinated.

Howard and his Mexican wife Maria are now both gravely ill with COVID. Howard was medevac(k)ed back to the States yesterday in critical condition with coronavirus pneumonia. So tragic. So unnecessary. I'm sure that Howard has that extra information he was waiting for now, and wonders why he didn't just listen to those who already knew it.

What data are you waiting for?
 
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We Never Know

No Slack
And yet it makes a huge difference to credible experts in the field, i.e., to those actually capable of evaluating the statistics. That you deem yourself to be competent to counterpose your "analysis" to that of the medical community strikes me as more than a little incredible.


Not all opinions are created equal. Again, some are ignorant to the point of being malignant.

But, since you seem so intent on sharing your opinion, perhaps you'll allow me to share mine: the more uninformed people who think like you, the more innocent people will die.

"the more uninformed people who think like you, the more innocent people will die"

So a person who would like to know more about the study and its participants are why more innocent people die? That's about the most ignorant statement I've ever heard.
 

We Never Know

No Slack
Would you be able to evaluate the study if you saw the data you mentioned? It's a learned skill. If you can and want to do so, you generally need to find the original study published in a reputable journal, where such data is provided

Your choices are these:

[1] Look at the original published study. Go to the methods and materials section, usually right after the abstract, and look at how the study was designed. Was it randomized, and controlled. Was it sufficiently powered (enough people studied) to achieve statistical significance? You'll need to know how to evaluate such data to do that, but you can come to your own conclusions and compare them to the study's conclusions. If available, you can review criticisms of the study if any (peer review).

[2] If you can't or don't want to do that, the next best thing is to identify trustworthy sources. If you know how to do that, and have accurately identified the experts, you can trust them provisionally. This is different from the genetic error, which judges the correctness of the conclusion of an argument by its source. You know that the conclusion may be flawed, but you also know that your expert's opinion is more reliable than your own, and if you are a good judge of who is trustworthy (even if not always correct), it is rational to decide that the experts are probably correct, as when you consult an attorney or physician. The genetic error says something like, "My doctor has the correct diagnosis because he's a good doctor" rather than, "My doctor is more likely correct than I am, and I will defer my judgment to the expert."

[3] Do neither of these things and just ignore the study, or accept or reject it on faith.

Let's look at a study at Effects of intercessory prayer on patients with rheumatoid arthritis - PubMed :

Effects of intercessory prayer on patients with rheumatoid arthritis

D A Matthews 1, S M Marlowe, F S MacNutt
South Med J . 2000 Dec;93(12):1177-86.

Abstract

Background: Many individuals pray during times of illness, but the clinical effects of prayer are not well-understood.

Methods: We prospectively studied a cohort of 40 patients (mean age, 62 years; 100% white; 82% women) at a private rheumatology practice. All had class II or III rheumatoid arthritis and took stable doses of antirheumatic medications. All received a 3-day intervention, including 6 hours of education and 6 hours of direct-contact intercessory prayer. Nineteen randomly selected sample patients had 6 months of daily, supplemental intercessory prayer by individuals located elsewhere. Ten arthritis-specific outcome variables were measured at baseline and at 3-month intervals for 1 year.

Results: Patients receiving in-person intercessory prayer showed significant overall improvement during 1-year follow-up. No additional effects from supplemental, distant intercessory prayer were found.

Conclusions: In-person intercessory prayer may be a useful adjunct to standard medical care for certain patients with rheumatoid arthritis. Supplemental, distant intercessory prayer offers no additional benefits.​

There's your data in the methods section. Forty people were studied. Their average age was 62, all white, 82% female. All had training and one-on-one direct prayer sessions for a total of six hours, but about half also had prayer from a distance. The abstract doesn't tell us if the patients knew this. Specific disease markers not named were measured four times over a year.

What do you think? Do these data support the conclusion? As I suggested, one ought to have some familiarity with doing this before saying, "Show me the data." Here's my assessment:

There is no control group for direct prayer. It is probably assumed that patients not in the study would be expected to be the same in six months, but maybe modern treatments make improvement over six months common anyway. Is forty people enough to reveal a difference between prayer and no prayer if you did include a control group? Statisticians generally provide those answers, which are generally included in the abstract, but not this time.

Although the study had no control group, those in the study were divided about evenly into those who received direct and remote prayer, and those that received only direct prayer. Is that enough people to conclude that the lack of effect of remote prayer was due to there being no effect? Perhaps if the study had been 2000 people, the groups would have begun to separate.

Look at how weak the conclusion is. Prayer might be useful. Wasn't that assumed before going into the study? If that weren't already believed to be possible, why do the study? Can we be sure that the second sentence in the conclusion is correct? I'd have preferred that it be worded that the remote prayer didn't lead to a detectable difference, not that it offers no benefit.

And what about the Southern Medical Journal? I'm a retired physician, and never heard of it, but that doesn't mean that it isn't reputable. I didn't find much on it, but it looks a little suspect to me. The Southern Medical Association publishes it, a professional organization said to be dedicated to educating clinical physicians

Judge for yourself: Southern Medical Journal - Wikipedia and Southern Medical Association (SMA)

I'll defer to the scientists present on RF who have actually been involved in published studies to tell you more if there is more to be said (I only read them), but I concluded that this study has no value and reveals nothing. Notice that this is me visiting the first category above, but putting myself into the second anyway, since there are several posters here on RF whose judgment I would defer to if they told me I had it wrong, but were unable to explain why in a way that I was prepared to understand.

Given your comments, I'd ask myself if I were really looking for scientific guidance or not. I hear so many people that I believe are simply more afraid of the vaccine than the virus that they just don't want it, but don't feel like that's an adequate answer. So, they give reasons to justify the choice, as if those reasons were what led the to dispassionately and rationally conclude that they should wait on the vaccine. They say they are waiting for more information, when there is enough information now to decide in favor of being vaccinated. Sure, there's a long shot possibility that in the end, more people will have died from an as yet unknown complication of the vaccine in five or twenty years than from the virus, but that is not a reason to choose to risk the virus unvaccinated instead.

Remarkably, nobody I know has died from COVID yet, but just now, there is one about to. He's an acquaintance named Howard, a retired attorney and expat living in Mexico like I do who I was in a play with a few years back. He's an eccentric and impulsive guy, on his fifth or sixth wife, third in the eight years I've known him. He didn't want the vaccine. He was waiting for more information, he said. He wanted to see how others did with the vaccine first. We were his guinea pigs, he thought, not realizing that he was in the "study" as well as part of the control group, the unvaccinated.

Howard and his Mexican wife Maria are now both gravely ill with COVID. Howard was medevac(k)ed back to the States yesterday in critical condition with coronavirus pneumonia. So tragic. So unnecessary. I'm sure that Howard has that extra information he was waiting for now, and wonders why he didn't just listen to those who already knew it.

What data are you waiting for?

I may or may not understand it more but at least I would know more about the study which can't hurt anything by knowing.

Take the study you posted. At least you know the average age group and gender. That's better and will give the reader more understanding than just 40 patients.

For conversation lets say a study consists of 1000 people.

400 are female's.... That excludes me

Of the 600 left..
250 are over 65.... That excludes me
275 are under 40.... That excludes me
175 have underlying health issues... That excludes me
125 drink regularly.... That excludes me
200 have a poor diet(over/under weight).... That excludes me.

So yes I would like to know more about the participants to see where I may fit in.
If that's a crime, I am guilty!
 
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We Never Know

No Slack
Which ones have you read?

Not any that lets be know how 60 yearish male's in good health and a good diet fare against covid. If you have any be kind enough to link them.

Look I know its deadly. I had it. It hit me no worse than a common cold. I'm not saying to anyone don't get vaccinated.
If you're at risk in any way or fear it, by all means go get the vaccine.

For conversation lets say a study consists of 1000 people.

400 are female's.... That excludes me

Of the 600 left..
250 are over 65.... That excludes me
275 are under 40.... That excludes me
175 have underlying health issues... That excludes me
125 drink or smoke regularly.... That excludes me
200 have a poor diet(over/under weight).... That excludes me.

We know several variables(some I mentioned above) contribute to the severity of covid. So yes I would like to know more about the participants to see where people like me may fit in.
If wanting to know that is a crime, or makes me an anti-vaxxer, or a heathen, or whatever.... Then I am guilty!
 
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