Airplane! has a lot of great quotes:
[as the plane prepares to take off]
Lady - Nervous?
Striker - Yes.
Lady - First time?
Striker - No, I've been nervous lots of times.
Attndnt - Excuse me sir, there's been a little problem in the cockpit...
Striker - The cockpit?!... what is it?
Attndnt - It's the little room in the front of the plane where the pilots sit, but that's not important now.
Striker - I flew single engine fighters in the Air Force, but this plane has four engines. It's an entirely different kind of flying altogether.
Rumack, Randy - [together] It's an entirely different kind of flying.
From Top Secret
Nick - Are you in some kind of trouble with the police?
Hillary - Some things are better left unsaid.
Nick - Like what?
Hillary - Well, you know, sometime when you blow your nose into a tissue and you put it in your purse, then a little while later you have to reach in there for your lipstick or something and your hand gooshes
From Maybe Baby, this exchange made me laugh:
Lucy - 41% swimming in the wrong direction.
Sam - They're in a plastic pot. How are they supposed to know what the right direction is?
Lucy - Conclusion...
Sam - I've got slack, stupid sperm, that's the bloody conclusion. That stuff's been dawdling back up my dick all these years. Banging into each other, getting their abnormal tails tangled.
And I think it's safe to say that the entirety of V for Vendetta and Fight Club were very good quotes.