I don't realize parts of people's sex don't match up unless they're intersex, then I'm perfectly happy to do so -- because they were born that way.
And, biology isn't like a debate, it doesn't matter what you think.
There are some odd exceptions like chimeras or whatever, but for the most part gender = chromosomes. Everything else is fantasy, and it's about as real as calling yourself a vampire. Though, don't get me wrong -- I don't hate those people, I think they're troubled, need help (a lot of it), and it's a complex problem.
I understand dysphoria, but I also understand it's a psychological problem that needs treatment. We don't cure the drug addict by giving them more drugs, or the obese by supplementing their cheeseburger intake. No, we cut them off, correct them and encourage the right behavior, which some people have a hard time learning. The other thing that irritates me is that even after transgenders go through surgeries, treatment, and whatnot they still kill themselves frequently and many desire to revert. If this was solving their problem they'd be freaking happy and move on, but that's not what's going on. I know quite a few transgenders, and man they're all pretty sad folks. So, if that's all I got to go by, I'm not down with what's being done in this realm at all. Politics, white knight points, and whatever be damned.