Sarcosine- a new treatment for depression: "A clinical study showed Sarcosine to be significantly more effective in treating Major Depression (substantially improved scores on the Hamilton Depression Rating Scale, Clinical Global Impression, and Global Assessment of Function) than
Citalopram over a 6-week period. Sarcosine-treated patients were much more likely and quicker to remit and less likely to drop out of the study. Sarcosine was well tolerated without significant side effects"
https://en.wikipedia.org/wiki/Sarcosine
A testimonial:
Half an hour in, I'm not sure if I notice anything. I feel a bit clearer, a tendency to rub the feet, perhaps some excitatory effects. Nothing ontoward.
An hour in I just now caught myself doing an overdue gardening chore in the hot sun. My primary negative symptom is physical passivity. This may be wishful thinking but it does appear to have an activating effect in me that is distinct from a stimulant. I'm not significantly stimulated or sedated, feel kind of OK and maybe feel a bit clearer and more active.
On schizophrenia.com 70% of people polled said it helped them.
Two Hours In I feel more mentally active. no real side effects. I might be one of those who can make due with 1 gram a day. Gonna make a few capsules for easy dosing.
Three Hours In I, wow, am definitely experiencing effects here. I am more physically and cognitively active and seem to have more motivation, theres more going on, but not in a stimulant way. It feels activating rather than that is presents as a stimulant effect. This is no coffee, no cathinone, it feels like a nootropic, one that WORKS, something that improves the function of my brain in general rather than has a stimulant effect. The first day! I made a bunch of capsules of 800+mg each for easy dosing. I'm gonna try one a day, see what it does and how it effects me longterm as this substance, just like antidepressants, will build up for about 8 weeks. 800mg a day may be just what the doctor ordered
Four Hours In Its a hot day and I'm not good with heat in general but, I'm having notable orthostatic hypotension. If I sit for a while, then get up, I have to sit again because of dizziness. Ack, I hope its mostly the weather.
Five Hours In I did a whole lot of physically active stuff despite the hot weather and the tendency to orthostatic hupotension. I feel mentally alert, yet not like I took a stimulant. For me, this is an active nootropic. This may actually do me quite some good, I'm intrigued. If side effects stay low this is something I want to explore. Sure beats coffee!
Six Hours In Stil alert but less acutely so. I'll end the report here, its been quite promising.
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ONE MONTH LATER!
I been doing 800mg capsules ("00" caps), one each morning, for one month now and I notice definite effects.
I'm more active and psychologically versatile, my speech indeed has gotten richer, even typing speed has increased and i notice a marked decrease in particularly outlandish thought.
I do not feel psychologically or spiritually castrated and experience no real side effects.
All it does is benefit me, and to the point that I will stay on this and perhaps will up the dose later. Its GOOD as it is though, I don't want to be without it.
Unlike antipsychotics this is a noortropic, this makes my brain function
better, not
less.