Of course but many think it's perfectly harmless no matter how they partake and it is not.
If you make a tincture or other form of extract, there is no inherent physical harm in partaking. Any potential psychological harm is based on the psychological disposition of the person who takes it, not in the inherent qualities of the chemicals in the plant. If I remember correctly, cannabis contains both psychotic and anti-psychotic compounds.
How many smoke tobacco versus pot. It's simple math.
Or not. There are lots of varying chemicals in both plants. One of the biggest factors in the toxicity of tobacco smoke is tobacco specific nitrosamines, which, if I remember right, increase based on the method of processing the tobacco. This includes how long the tobacco is fermented and how it's cured; fire-curing tobacco increases the levels of TSNs in tobacco and the longer it is fermented, the more TSNs build up.
Nicotine also constricts blood vessels, which makes it harder for the body to get rid of toxins, while THC dilates vessels, making it easier for the body to get rid of toxins. There are so many different factors that go into the development of disease, like how smoking is very often paired with heavy drinking, further reducing the immune system's capacity. Also, THC and other cannabinoids have been shown to stop or prevent tumor growth.
Not just simple population comparisons. Greece and Japan have more tobacco smokers than the USA but lower levels of heart and lung diseases.
Anyway, I also dont like the argument that, because it's natural, it's safe. Still, it is just a plant, minimal to no processing is needed to make it ready for use and, unlike natural, toxic substances like certain other plants and mushrooms, it is not toxic to humans, so there's not great reason to control it, IMO