In 2022, two papers were published on research favoring the RNA World hypothesis of the origin of life on Earth.
In the first paper it was demonstrated that RNA could evolve and diversify leading to ever increasingly complex interactions between replicator molecules.
Evolutionary transition from a single RNA replicator to a multiple replicator network - Nature Communications
This was a long term experiment with RNA from E. coli encased in water-in-oil droplets. Heat and additional nucleotides were provided and over time the original sequences mutated and distinct lineages formed. This mutation and diversification occurred at varying rates indicating variation in fitness for the resultant sequences. Sequences of different lineages interacted with each other in unique ways. This complexification of replicators and the development of complex interactions could eventually lead to the origin of living things.
The second paper deals with the potential RNA to co-evolve with peptides in the first steps leading to living things.
A prebiotically plausible scenario of an RNA–peptide world - Nature
Edit: Thank you @ratiocinator for pointing out that I hadn't linked the first paper.
In the first paper it was demonstrated that RNA could evolve and diversify leading to ever increasingly complex interactions between replicator molecules.
Evolutionary transition from a single RNA replicator to a multiple replicator network - Nature Communications
This was a long term experiment with RNA from E. coli encased in water-in-oil droplets. Heat and additional nucleotides were provided and over time the original sequences mutated and distinct lineages formed. This mutation and diversification occurred at varying rates indicating variation in fitness for the resultant sequences. Sequences of different lineages interacted with each other in unique ways. This complexification of replicators and the development of complex interactions could eventually lead to the origin of living things.
The second paper deals with the potential RNA to co-evolve with peptides in the first steps leading to living things.
A prebiotically plausible scenario of an RNA–peptide world - Nature
Edit: Thank you @ratiocinator for pointing out that I hadn't linked the first paper.
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