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Study finds bursts of rapid aging at 44 and 60

We Never Know

No Slack
According to a small study this is what you youngsters here have to look forward to :p

Study finds bursts of rapid aging at 44 and 60

"The human body doesn’t age steadily throughout middle age and, instead, goes through bursts of rapid aging typically at around age 44 and again at 60, according to a new study published Wednesday in the academic journal Nature Aging.

Stanford University researchers tracked age-related changes in more than 135,000 types of molecules and microbes in samples collected every three to six months from more than 100 adults between the ages of 25 and 75 years old."

Researchers gathered more than 5,400 blood, stool, skin nasal swab and oral swabs as part of the study, and as a result were able to track more than 135,000 different kinds of chemical compounds, bacteria and cell parts affected by aging.

Scientists found the abundance of these molecules and microbes did not change steadily over time but rather increased and decreased rapidly around two ages — first around the onset of a person’s 40s and again in their 60s.

While researchers found evidence that cellular changes are more likely to occur around these ages, more work needs to be done to figure out why..."

 

VoidCat

Use any and all pronouns including neo and it/it's
I've already passed both those age stages so it can slow down anytime now lol
Similar note: I dont get why folk dont like the way aging looks. There's this thing going around about tiktok surgeons trying to make old folk look super young and they basically take all the character out the faces. Old folk often have a lot of character in their faces wrinkles and all. And it shows that they lived long which means theyve survived this long. Great knowledge there to be heard.

But yeah disabilities come with it. Yet if you don't age that means you died young. So there's that.
 

We Never Know

No Slack
Similar note: I dont get why folk dont like the way aging looks. There's this thing going around about tiktok surgeons trying to make old folk look super young and they basically take all the character out the faces. Old folk often have a lot of character in their faces wrinkles and all. And it shows that they lived long which means theyve survived this long. Great knowledge there to be heard.

But yeah disabilities come with it. Yet if you don't age that means you died young. So there's that.
Its not looks I'm talking about. Its the aches and pains of getting out of bed in the mornings that get worse with age.
 

Saint Frankenstein

Here for the ride
Premium Member
Its not looks I'm talking about. Its the aches and pains of getting out of bed in the mornings that get worse with age.
I already have a lot of physical pain due to injuries and not taking care of myself for most of my life. But I'm actually in the best shape I've ever been in and have more energy than I ever have before. I even have muscles now and I didn't even realize that before because I was always fat throughout my life. Never thought I'd have muscles. Lol. But I have been walking and working my *** off for the last few years. Just carrying your groceries home over half a mile in a backpack can make a lot of difference.
 

Quintessence

Consults with Trees
Staff member
Premium Member
Adding a few addendums because as someone who is aware of research methodology I had some big questions about methodology because it is important to acknowledge the limitations of a given sample frame. This is not a multi-national study, but a study done from the population of the State of California. To their credit, ethnic backgrounds were diverse and representative, as were age and sex demographics so there's probably not a bias issue there. We would want to see similar studies from other parts of the world before assuming findings are broadly applicable to the entire human species globally (we know that aging interacts with various environmental and dietary factors both of which vary widely in different locations).

Another thing I immediately thought of and the authors acknowledged and rightly investigated is this:


Although confounders, including sex, were corrected before analysis, we acknowledge that the age range for menopause in females is typically between 45 years and 55 years of age, which is very close to the major transition points in all three clusters (Fig. 2c). Therefore, we conducted further investigation into whether the menopausal status of females in the dataset contributed to the observed transition point at approximately 55 years of age (Fig. 2c) by performing separate clustering analyses on the male and female datasets. Surprisingly, both the male and female datasets exhibited similar clusters, as illustrated in Extended Data Fig. 4a. This suggests that the transition point observed at approximately 55 years of age is not solely attributed to female menopause but, rather, represents a common phenomenon in the aging process of both sexes.
 

Kathryn

It was on fire when I laid down on it.
Well, at 62 I have passed both those markers and I can tell you what I tell other people, "We no longer bounce at this age." Which is so true.
 
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