I've been reading a little about Logical Positivism vs Scientific Realism, in Adam Becker's excellent history of quantum physics, entitled "What is Real?"
Each of these competing philosophies of science inevitably ran up against the paradox of perception, and the impossibility of neutrally observing external reality as it exists, independently of the process of observation.
It follows that any fully objective perspective of the natural world must, by definition, be supernatural. A God's eye view, as it were, a consciousness capable of knowing the true nature of the universe from within and without. Does such a consciousness exist? Millennia ago, the writers of Vedic scripture certainly thought so.