I self-published my second book in late October, and am working on my third, which I hope to release in September of next year.
As per the OP, both books have been interesting experiences for me. The actual publishing process was relatively easy -- once I had the manuscript and cover art lined up. I used Amazon, which was recommended to me as the easiest route to take for a first timer.
For me, the most disagreeable part of the job has been promoting and advertising the books. I used to love that sort of thing, but it's an old, familiar, and boring game now, and I'd rather be doing most anything besides it. Fortunately, I don't need the sales for income.
The most pleasing surprise has been that after I published my second book, a few people have written to me saying the book has the "feel of literature" or is "literary". I didn't get that with the first book, and I take words like those as compliments.