This to me becomes a very subtle and complex question for me based on my life. In some situations the answer was yes and sometimes apparently no. One work decision I made appeared to be utterly wrong and led to me being fired. I was told later that I had to make that choice to balance karma from a previous life. So, yes, I was guided in that situation but it did not seem so at the time.
Looking back, I remember a major decision I made regarding work that I later regretted. That was when I decided to resign from a federal job I had for 10 years to go back to school and get a second MA degree in counseling psychology. That extended out the time I could retire out 10 years but at the time I did not think about that as I just wanted to go back to school.
At that time I thought I wanted to be a counselor but it never worked out for various reasons. However, within a few months of quitting my federal job I procured a state job in the same field in order to work my way through grad school and I remained in that job ever since. I now have 44 years working for the federal and state government. I could have retired three years ago but I don't really want to retire so what I was regretting a long time ago never turned out to be an issue. I took what was in my federal retirement account and got a Roth IRA so I ended up with a lot of money that can be used in retirement if I never need it. Would I have retires=d much sooner if I had stayed with the feds? Only God knows, but obviously that was not meant to be.
As an aside, if I ever do retire I can use my counseling degree to work part time although I do not need the money so it would just be because I want to help people.
As I told my boss this week, I have never been fired from a job in my whole life, I always left voluntarily, so looking at being fired simply because I will not comply with the state employee vaccination mandate is very disconcerting to say the least. Of course if faced with that choice I could choose to retire rather than being fired, but there is a good chance I will not be faced with the choice since I am seeking an accommodation through my counselor.
That might be the experience of what is called the "void" or "dark night" in spiritual literature. I'm not sure if this is your state or not, but if it is, maybe it will help:
A man sits
by a tomb,
head bowed,
lost in thought.
Tears
at a life ended.
No where to go,
nothing to do.
Former joy
is now ashes.
Former life
is now silent.
Surrendering,
he merges
with the cold, still earth.
Dawn's mist
invokes quiet and peace.
Existence is an eternity
of patient waiting.
Slowly felt:
dawn's earth warming light.
From the tomb,
a seed opens;
a flower begins
its slow sunward journey.
It is not quite that bad but thanks for the poem. As I indicated in my OP I can use all the help I can get and it is not as if my work situation is the only problem I am facing. Many other issues have been on hold for many years and now they are all coming down on me like a building that is collapsing.