There are legitimate claims that we can make about the unknown and the unknowable. And there are legitimate arguments that can be posed about what we think we DO know.
Maybe it's time to accept this. To accept that we humans not only don't have all the answers, but that we may not have ANY of the answers.
Of course we don’t have all the answers.
Scientists don’t or shouldn’t make assumptions that everything are known in science.
The great thing about science, is there are always more to learn, more to discover. Science itself is a learning process, and it is call progress.
Like Columbus said, we learn more over time, when we developed better tools tossing with search and research:
Historically speaking, it was quite recently when humans couldn't observe microorganisms, or galaxies. As our methods and tools became more sophisticated we learned more. Became more able to observe and learn and understand.
His example about galaxies is a good one.
When Galileo made his own telescope shortly after its invention, he didn’t have all the answers. Nor did other astronomers after him, like Newton, Kepler, Messier, Herschel, all had better telescopes before each one, some of their identification of objects.
All astronomers before Edwin Hubble in 1919, thought objects like Andromeda, Triangulum, Virgo A were nebulas, not galaxies. Pre-Hubble astronomers all thought that the Milky Way was the only galaxy in the universe, because their telescopes could only allow them so much.
When Hubble used the largest telescope at that time in 1919, the Hooker Telescope at Mount Wilson Observatory, his discovery changed everything: there were many galaxies out here, and the universe was even larger than Hubble thought.
The discovery had also changed our view with cosmology, and in the 1920s 3 independent astrophysicists - Friedmann, Robertson and Lemaître - came up with similar concept: the expanding universe model, later known as the Big Bang model (late 1940s).
Then radio astronomy gave us the technology to observe even more galaxies. And we were able to learn even more with space technology.
Science is accumulating knowledge, where past discoveries are corrected or replaced, all depending on the available evidence discovered.
Science isn’t a fixed knowledge, there are always more to learn.