When I say designer, I mean technical designer/engineers of some sort, whether that is within computer software or robotics etc. Which to me is simply because if you can't do these things, you are simply not qualified for what is needed. Im not saying that every single job is going to go away, but I think you could see it sort of like a person today, that is unable to use or work with a computer, but I think these requirements will escalate in the future, so a huge amount of jobs will require people to be able to this, and if they cant, then they will just hire someone else, because there will be enough to chose from.
For instance, self driven cars. These are coming sooner or later, its just a matter of time, they are also working on ships, trains (Already here), planes (a lot of this is already automated) so when cars comes, or if its drones or whatever. All people that are delivering goods or transporting stuff or people will be obsolete and will have to move to other sectors. And as you say these don't have a technical background, but the chance is that whatever jobs they have to jump to, also requires a technical background, and that is simply one sector.
So as you say not all people are capable of these things, but since when have a company ever cared about that? They are there to make a profit, not charity and they will get rid of people, if they can earn more from it. It have always been like that, so I don't see why they would care?
The only time they will care is when there is not enough purchasing power to buy their stuff, and then **** will hit the fan so to speak, because should that happen then the economy will collapse.
Just what I think we can expect in the future and why humans can't compete (just some short videos):
And the list goes on, there are people working on some crazy (cool) stuff out there