I'm talking about virtual particles, they pop into and pop out of existence, cause is unknown.
But just because cause is unknown is not proof that things can be uncaused.
I don't know of any other events for which cause is unknown?
First of all, "proof" is not part of any scientific theory. A theory is just a model of reality - one that successfully predicts what we should expect to observe in nature. So yes, nothing is final. There may always be new discoveries, leading to changes to the model. But the
evidence is that there can be uncaused events.
I don't think you are right in saying that in this case the "cause" is "unknown". In the theory, there is
no cause required. It's all part of the concept of indeterminacy, which is at the heart of QM (Heisenberg's Uncertainty Principle being the best known expression of it). In QM, some properties are simply not even
defined exactly, i.e. they have no exact existence. This is a feature of the maths of the theory, which I still dimly recall from my university days: non-commuting operators, Fourier transforms and so forth.
There have been attempts to get rid of quantum indeterminacy - thereby recovering a deterministic universe, of the kind Newton and Einstein would aesthetically prefer - by way of a variety of so-called "hidden variable theories". However none of these has worked. So at this point in human history it really looks as if quantum indeterminacy is a genuine feature of the world.
On the question of examples of uncaused events, the decay at a particular instant of an atom of a radioisotope is another popular example. The radioactivity can be expressed as a probability of decay within a certain time interval, but there is nothing that makes a particular atom decay at a particular moment. (My understanding is you can model it as being induced by vacuum fluctuations, but all that does is push the issue back onto the lack of cause for vacuum fluctuations to fluctuate the way they did, in that place, at that instant. So you still can't get away from quantum indeterminacy.)