Humor is a wonderful coping mechanism, but there is a fine line of laughing with and for someone, as opposed to laughing at someone.
Some things, despite claims in this thread to the contrary, aren't worth joking about.
It's hard to say anything without offending someone which is why most of my jokes are self deprecating but I can't help wondering if the world would be a better place if we were all a little thicker skinned and not so easily offended.