tas8831
Well-Known Member
I already provided a source that shows that 3 million mutations where crucial (ie beneficial) in the evolution of humans, what else do you want?.
No, you did not. The article you referred to indicated that this 3 million "may" contain relevant mutations:
"However, as many as 3 million of the differences may lie in crucial protein-coding genes or other functional areas of the genome."
But no, you go ahead and keep embellishing this one result of your keyword search technique.
Still waiting for you to explain how many fixed beneficial mutations are required for any trait you choose. But that would require you to understand how genes and development work, so...
Anyway, even if all 3 million were totally beneficial, that is different from 50,000 being "too few" or whichever number you are dreaming up today.
An analogy - a human needs, say, 500 calories a day to survive. If that human takes in 1000 calories, they will survive and then some.
Get it?
But thanks for undercutting the whole "Haldane's dilemma' thing, which only allows for a couple thousand.
I am sure creationists like ReMine will welcome the news that you have destroyed their careers.
You're a funny guy - creationist tactic #72 - when you are getting spanked, try to set yourself up as a brave martyr...... Your supposed "reply" is pathetic missleading and dishonest .... Then you disguised your answer with a long series of irrelevant strawman arguments personal attacks irrelevant stuff and other red herrings
But hey this is an open forum , anyone can see your reply and judge whether if I provided a good response or not.
You mean you understand that I accept the evidence that most mutations are neutral.Granted, my mistake was assuming that you where a selectionist , implying that most (or atleast a big portion) of mutations would have to be positive. But ok now I know that you are a neutralist.
So cute how your whole argument has changed - but not as cute as how you keep misrepresenting that article.But you still have to explain the 3 million mutations that where benefitial. 50,000 is still too few.
What really impressed me is that in your mind you actually think that you made a valid point.
How do you go from "achondroplasia" to "therefore 50,000 mutations are enough to explain the differences between chimps and humans? And there is no room for reasonable doubt anyone that question my dogma is stupid"
Golly, I thought I explained it pretty well - maybe if I paste in in bold?
1. There really are no 'brand new' traits that humans possess that chimps do not, indicating that our common ancestor also that the same basic traits
2. Therefore, we only need to "tweak" existing traits, and tweaking an existing trait does NOT require some large number of beneficial mutations
3. Support for this - point mutation in the FGFR-3 gene causing achondroplasia - altered limb-to-trunk proportion, altered facial characteristics, reduced joints, etc. All from one mutation. Reminder - I am NOT presenting this as a beneficial mutation, just the reality that MULTIPLE phenotypic traits can be altered, in this case, by a single mutation.
The fact that you cannot tell us all how many fixed beneficial mutations are required for ANY of the unnamed traits that had to have been affected tells me that you have nothing but rhetoric and misrepresentation.The fact that you seem so sure that 50,000 mutations are enough made me believe that you had something better.
The problem is that you where supposed to show a benefitial mutation.
Was I?
Tell you what, Skipper - here is a link to the Human Genome browser:
UCSC Genome Browser Home
Take your impressive genetics knowledge and do what no other creationist has even tried to do -
FIND A BENEFICIAL MUTATION in there. For any trait you believe had to have been altered by such. Go ahead. Then explain to me how many such mutations were required for that trait to be what it is in humans and how it differed from a common ancestor.
I can wait. I've been waiting for ReMine to do it for 25 years.
Many, if not most mutations do this - you would know this if you were not so ignorant of the subject matter. Look up Pleiotropy..... Or even more specifically you are suppose to show that benefitial mutations usually tend to alter multiple traits.
If you understood basic genetics, you would realize that you don't have a point.If you could show that a single mutation was responsable for multiple benefitial traits like bipedalism, brain size, and language etc you would have a point....
Why would you think that I think that 'traits' like brain size AND bipedality would be affected by a single mutation?
In the achondroplasia example, the obvious implication was that a single mutation can affect LIMB development (among other things) - LIMBS are made up of bones, muscle, nerves, skin, etc. I know of many creationists that have insisted that each of those (bones, skin, etc.) would all REQUIRE their own specific beneficial mutations.
This is stupid. Do you admit that altering a limb would NOT require a suite of specific mutations governing every aspect of the a limb?
BTW, I can also provide examples of traits that require more than 1 mutation, I don't know why would this be relevant, but if in your mind this would dispute your claim I would be happy to provide an example. ...
Please do - but do admit that you understand that it is not universal, seeing as how I have shown this is not the case.
Let me guess - you will be paraphrasing or linking to Behe's big blunders?
Oh - a reminder that in a post you ran away from, I spanked you on yet another issue:
Putting God's Design In Perspective
...
Answer this honestly - does all of your knowledge of genetics come from creationist websites?
It looks like you are completely unaware of the following:
1. The timing of gene expression can produce phenotypic modifications during development
2. the extent of expression can alter phenotype
3. 1 and 2 above do not require ANY change to the coding gene involved at all.
Here is an example:
A single p450 allele associated with insecticide resistance in Drosophila.
"Transgenic analysis of Cyp6g1 shows that overtranscription of this gene alone is both necessary and sufficient for resistance. Resistance and up-regulation in Drosophila populations are associated with a single Cyp6g1 allele that has spread globally. This allele is characterized by the insertion of an Accord transposable element into the 5' end of the Cyp6g1 gene."
So, what happened here is that a transposon inserted itself in promoter/enhancer region of a gene and caused it to be over-expressed. This conferred an adaptive benefit, now fixed in these populations of Drosophila.
Single mutation, altered phenotype, no mutation in the gene itself.
A single paper destroys 3 of your claims/implications.
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