I do not see the world as some victim of human persecution. Suffering is a by-product of evolution as is extinction. 'Greed' is a moral dilemma which threatens our own species, not to be confused with natural conservation. Taking land from animals is a land management decision not greed. Killing and replacing other species is natural not unnatural. Driving them out, killing them, being annoyed with them: very human. It is the voice of evolution speaking. Those species which are compatible with us we like to keep, and those that are incompatible we do not keep. But. We should make sure we don't eliminate ourselves, because that would be stupid.
I don't know about the 300% number but have heard it somewhere before. The destruction of species is undesirable usually, but on the other hand I'm not going to live in a cloud of mosquitoes. I just am not, and sometimes it is them or us.