His Holiness the Dalai Lama (HHDL from now on in this thread) teaches that if science conflicts with scripture, go with science. Before getting into why he says that, what do you think?
I think HHDL is one smart cookie. His full quote is If scientific analysis were conclusively to demonstrate certain claims in Buddhism to be false, then we must accept the findings of science and abandon those claims.
I think this meshes nicely with what the Buddha is quoted as saying (and I refer to frequently): "Do not believe in anything simply because you have heard it. Do not believe in anything simply because it is spoken and rumored by many. Do not believe in anything simply because it is found written in your religious books. Do not believe in anything merely on the authority of your teachers and elders. Do not believe in traditions because they have been handed down for many generations. But after observation and analysis, when you find that anything agrees with reason and is conducive to the good and benefit of one and all, then accept it and live up to it."
The reason I think this is because scriptures of virtually any religion were composed in historical times devoid of a scientific understanding of the world and universe. Many of them leave themselves open to interpretation and application for the times.