I already did.I am well aware. May I suggest you read some of my previous posts?
When I make a long post like these ones, I generally make them as self-contained as possible, meaning that they can be readable to whoever happens to read it rather than just one or two people that read through the whole thread carefully. So if I describe the function of something as it relates to what I'm saying, it's not necessarily an indication that I don't think you know that particular fact, it's because I'm writing it for anyone that happens to read the post.
For a given thread, the number of views will be an order of magnitude greater than the number of posts.
But keep in mind that most of the body's cholesterol is produced by the body, and it self-regulates.Yes, LDL and HDL are both forms of cholesterol. The function of LDL is to bring cholesterol to various tissues. The function of HDL is to remove cholesterol from tissue to the liver for disposal.
The link between a high (healthy) level of HDL and lowered risk of heart-disease is well known.
Since the function of HDL is to remove cholesterol from tissue for disposal, then it appears that removing cholesterol reduces the risk of heart disease.
-The high cholesterol and saturated fat Inuit diet doesn't seem to increase risk of heart disease. Same thing for the French. They also don't eat a lot of inflammation-causing foods.
-This meta-analysis of studies in the American Journal of Clinical Nutrition concluded that "there is no significant evidence for concluding that dietary saturated fat is associated with a risk of coronary heart disease, stroke, or cardiovascular disease."
-The link between dietary cholesterol levels and cardiovascular problems is quite weak. (I don't necessarily agree with every single conclusion in that article, but there are 64 references and for a given statement in that article, they list the reference, which is why I'm linking it.) Like this reference, that says, "Based on these studies, the association between dietary cholesterol and coronary heart disease risk is, if anything, minor in nature."
-Keep in mind that a lot of studies are based on people in developed countries where the diets are highly inflammatory to begin with, with lots of processed oils, processed carbs, and factory farm animals. They're studying the dude that eats McDonald's or meat-n-potatoes for dinner, rather than a statistically relevant sample of people that eat very intentionally with fish, grass-fed beef, very high amounts of fruits and vegetables, and so forth. Increasing or decreasing dietary cholesterol when one has a highly inflammatory diet (seeing as how cholesterol specifically gets sent by the body to the inflammation damage), is not necessarily the same as increasing or decreasing dietary cholesterol when one has a healthy, non-inflammatory diet. (Inuit and French diets tend to not consist of inflammatory foods.)
-When I switched from a purely vegetarian diet to one that includes a bit more saturated fat and cholesterol and a bit less carbs in their place (occasional salmon and chicken, along with the other saturated fat sources I already ate in moderation like dark chocolate, nuts, and coconut oil), my HDL (good) cholesterol went a bit up, my LDL (bad) cholesterol went a bit down, and my triglycerides (bad) went a bit down, according to a comprehensive blood test. The were already at good levels, but they improved. One factor was that my diet became less inflammatory due to the addition of some fish (with moderately high cholesterol and saturated fat, strongly anti-inflammatory) and the reduction of some carbs (a bit less rice, pasta, with no cholesterol or saturated fat but inflammatory), and the maintenance of similar levels of other foods like nuts, beans, fruits, and vegetables. Although it was already at a low level of inflammation compared to the standard American diet, it became lower, and blood test results of cholesterol and triglycerides improved.
I'm not saying that cholesterol itself doesn't build up on artery walls due to certain conditions.This is because I am not arguing about that stuff.
From what I can make out, there are three claims being made:
1. Dietary cholesterol has no effect upon serum levels of cholestrol.
2. Amount of dietary cholesterol has no effect upon a person's risk for developing heart disease.
3. Cholesterol plays no role in the development of atherosclerosis.
I am not arguing 1 or 2. As mentioned in previous posts, I find it likely that these diets restricting cholesterol are over-blown and faddish. It also appears that there is respectable research indicating that the link between dietary consumption of cholesterol and heart disease is not perfectly correlated. I also have no doubt that statins are over-prescribed.
I am, however, arguing against Claim 3. The role of cholesterol (LDL) in the development of atherosclerosis is well-documented. Various studies indicate that cholesterol causes inflammation, which starts the plaque forming processes. And, regardless of whether cholesterol actually initiates the inflammation, LDL is a prime component in plaque formation, due to the fact that it becomes oxidized when it enters the arterial cell walls, which increases the inflammation, thereby attracting more stuff to come to that spot (including more LDL), creating the plaque.
The question is, what would make the body do that? Why would it keep making LDL to send cholesterol to the arteries, and produce less HDL cholesterol to take it back, resulting in a dangerous long-term build-up? The most consistent answer would seem to be the chronic inflammation itself. Focusing on the cholesterol, especially dietary cholesterol, is focusing on the body's response to the problem rather than the problem itself, as far as the data seems to suggest. So statins can help with heart disease because they're constantly trying to block the cholesterol, but an easier approach is to just not eat the types of food that make the body want to send all of that cholesterol to those places to begin with.
And a related question is- does dietary saturated fat and cholesterol have anything to do with the amount of cholesterol that actually ends up on artery walls, especially in a non-inflammatory diet?
And- if the body is responding to inflammation in such a way to send cholesterol to the artery walls, does eating less saturated fat and cholesterol improve that at all, do nothing, or even make it worse (such as perhaps by eating more inflammatory-producing carbohydrates in their place)?
More- why do some of the highest cholesterol diets in the world, statistically not have cardiovascular problems?
What are your thoughts on the various high cholesterol, high saturated fat foods that are anti-inflammatory, including grass-fed beef and especially sockeye salmon and other types of fatty fish? Sockeye salmon has high protein, a decent amount of saturated fat, high cholesterol, and is probably the single best thing you could eat for the purpose of reducing inflammation if that was one's particular goal.