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The question of God, a Creator, an Intelligent Designer is all speculation. It is a matter of personal individual faith and freedom to choose what to believe in in this experience of life as we know it. It's not a matter of science, physical brains or the mind. We can't know what happens to our minds once our brains stop functioning...we can only presume. And our presumptions may not be what we think.
How do you know if the mind cannot live without a brain ? One would have to die in order to know that, and since you are not dead you don't know. It is reasonable to speculate that the mind may not exist without a brain, but that is not definitive. It's a paradox. We can only know the answer to that once are brains cease functioning. As long as our brains are functioning we can only speculate. Plus, energy cannot be created nor destroyed, rather all energy changes from one form into another. This may apply to the mind as well. Or there may be another vehicle in which our minds transport into beyond our brains. There may be a universal mind which uses other types of vehicles to propagate itself. We won't know until our brains actually stop operating.