Of course!
God promised the Promised land to Abraham's descendants. Why do you think it wasn't given to Abraham right then?
Genesis 15:15-16 . . .. 16 But in the fourth generation they will return here, because the error of the Am′or‧ites has not yet come to completion.”
The people living in the promised land had descended into worship of their deities that included human sacrifice and the killing of children, which later Israel also succumbed to - for which they were made to suffer God's wrath also.
This is the reason God wanted these people erased. He has done it other places in the world, South and Middle America nations that practiced this are nowhere to be found today. They also were erased as cultures, though the people remain but without the disgusting customs. An American tribe also is gone - the Anasazi, whom also began this kind of practice. Beyond a certain level of evil, God erases such nations.