Was
leprosy (the medical condition, not the metaphorical affliction to which you're alluding)
literally viewed as the consequences of spiritual uncleanliness? If so, to what sort of spiritual shortcoming(s) would theists be obliged to view the medical condition of transsexualism (as Saint Frankenstein has asserted above) as a consequence of?
Many spiritual shortcomings. It wouldn't be necessarily labeling all as these types of "theists," rather any being that don't know the truth.
It would be as such as myself for an example: pondering over and seeking truth to why I'm in the overall average part of the pack when it comes to looks, finances, ability, knowledge, all of the variables and circumstances I am consciously placed in while others are are in theirs. Yet used to complain over the silliest things. The truth is, I had no free will over this, the ability and circumstances including health were not given or doing of myself, they were doing of a higher design, and when I came to truth and abundant life within... Any ignorance, arrogance, or pride of "self" deceased. My circumstances, ability, surroundings were not of my selection. I would trade my place in conscious life for that of another. Here is a good explanation:
When you see the truth, helping others is the only way. After the ultimate truth is discovered, spiritual people see others as themselves, so they love to help others. It is a natural way. We know that everyone is just like us. We put ourselves in other people's shoes and do the thing we would want done if we were really them, and that we can be like others in the future or have been in the past. Back to hell we go, in another physical body, and another experience of travailing pain until we discover the truth and abundant life. Hell must be experienced before paradise.
Spiritual being's see everyone as their own family. Truth is, we are one family of life on Earth. . spiritual beings are much more aware and feel other people's pain, pleasure, level of fullfillment more acutely.
The Christ conscious or Buddah conscious, etc.
He who experiences the unity of life sees his own Self in all beings, and all beings in his own Self, and looks on everything with an impartial eye.
Buddha
Cosmic energy (holy spirit) from the cosmos can significantly improve and heal ones mind and body and be of pure comfort to the afflicted to see the true treasures of life regardless of circumstances and be at genuine peace and contentment. The questions of why and why me dissipate. God's love and manifestation are in all alike.