New Genome Comparison Finds Chimps, Humans Very Similar at the DNA LevelOk so how many mutations do you think are needed to explain the differences between chimps and humans?
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The consortium found that the chimp and human genomes are very similar and encode very similar proteins. The DNA sequence that can be directly compared between the two genomes is almost 99 percent identical. When DNA insertions and deletions are taken into account, humans and chimps still share 96 percent of their sequence. At the protein level, 29 percent of genes code for the same amino sequences in chimps and humans. In fact, the typical human protein has accumulated just one unique change since chimps and humans diverged from a common ancestor about 6 million years ago.
To put this into perspective, the number of genetic differences between humans and chimps is approximately 60 times less than that seen between human and mouse and about 10 times less than between the mouse and rat. On the other hand, the number of genetic differences between a human and a chimp is about 10 times more than between any two humans."
I'd also point out that most of the changes have pretty minor effect and do NOT explain what most people consider to be relevant differences between humans and chimps. For example, chimps have lost some inflammation genes and humans have lost one that helps to prevent Alzheimer's.