This may fit somewhat with the subject. If not, oh well.
I remeber in one of my Economics classes we were talking about the value of information. Specifically, I believe we were talking about how much someone (say, a farmer) would pay to receive information about whether an event (say, an early frost) would occur. We went through the situation assuming that the information was perfect - if you were told it would happen, then it would in fact happen. We then looked to see if the information was imperfect - if you were told it would happen then it would have, say, an 80% chance of happening. Going from perfect information to imperfect information caused a very large drop in the value of the information, even at large probabilities of the imperfect information being right.
I kind of equate that with the difference between God and man. God has perfect information. He knows exactly what will happen under different circumstances and can make perfectly informed decisions. He knows for certain what would happen if, using the example that has been used in this thread - everyone but 8 people were killed in a flood. He is able to acertain which is the better option for everyone involved in every decision that is made.
Humans are dealing with imperfect information, usually with pretty small chances of being right. We have no way of knowing how our actions will affect those around us.
This being the case, we are bound by a different set of rules. We can't decide that the world would be better off if our neighbor was dead, because our information is imperfect. What's more, we are not in a position to be able to judge the things that God has done - or allowed to happen, however you want to look at it.