Yes. I think each nation should have absolute right to self-determination.
So you are against any type of treaty, any type of trade agreement, any type of conditional cooperation between any countries?
Because EVERY treaty signed, chips away at the "absolute" right of self-determination.
For example, if you enter a trade agreement to export food to country X, then there will be clauses therein about quality control etc. Like, it will for example not be allowed to use a certain type pesticide or hormones or whatever.
After you sign that treaty, the country will be prohibited from using such products in their food processing - at least in those foods destined for export.
ie, the country no longer has the "absolute" right of "self-determination".
It can no longer decide to use such products anyway. If it does so anyway, that would be a violation of the treaty. The outcome of which will likely result in blowing up the treaty.