Ok. I looked into. Researchers have found that even an
extremely small rate of arising of beneficial mutation rate is sufficient to overcome the genomic degeneration caused by accumulation of slightly deleterious mutations.
Dynamic Mutation–Selection Balance as an Evolutionary Attractor
"Hence any stable evolutionary state of a population in a static environment must involve a dynamic mutation–selection balance, where accumulation of deleterious mutations is on average offset by the influx of beneficial mutations. We argue that such a state can exist for any population size
N and mutation rate
U and calculate the fraction of beneficial mutations, ε, that maintains the balanced state.
We find that a surprisingly low ε suffices to achieve stability, even in small populations in the face of high mutation rates and weak selection, maintaining a well-adapted population in spite of Muller’s ratchet. This may explain the maintenance of mitochondria and other asexual genomes."
In infinite populations it has long been recognized that the balance between mutational pressure and purifying selection leads to a fitness equilibrium (Eigen 1971; Haigh 1978). Our analysis demonstrates that such an equilibrium also exists in a finite population, despite the action of genetic drift and Muller’s ratchet.