Controversy behind Rh negative blood type.
(Rh-negative, means that there is no specific proteins on the surface of red blood cells - membrane form.)
I don't know much about this, but even some science authorities claim that Rh negative blood type phenomenon proofs that some "external" influence changed pre-humans into humans.
Rh-negative blood is also not able to be duplicated or cloned.
Rh-negative mother mostly cannot bring Rh-positive offspring (it is possible now, with medical assistance). That characteristic is present only in human spices - some can say we are two spices in this regard.
Most Rh-negative people are from Europe. Another original group were the Eastern/Oriental Jews.
Rh factor is direct link to our Primate origin. Lack of Rh factor is almost impossible, because it needs whole different immune system to be involved later. To change immune system it would take hundred of thousands years.
Rh-negative blood holds recessive gene, so in a term of evolution it should evaporate until now.
Rh-positive people should be more resistant to some infections because of Rh membrane protective role.
So, there is a weak point in evolution theory. I wouldn't be much surprised if "someone" put his finger on pre-humans to create us.