Every scientific discovery is based on someone's guess. That is how the scientific method works. There is nothing factual in a guess. It is common sense. A new law is defined as, a guess - computation of consequences - comparison to nature. If it disagrees with nature, it is wrong, try again. As Dr. Richard Feynman most eloquently taught us, in his 1 minute lecture. Metaphysics, as Bunyip tells us, is a guess, a hunch. The exact starting point of the scientific method, that is used through the scientific community, is a guess. Indeed, Brian Cox supports Dr Richard Feynman explanation of the scientific method, that is, that it starts with metaphysics, a guess, a hunch, or in Einstein's case, a picture. Who would have thunk it? Knowledge is a wonderful thing, however, it is insufficient on its own. Without an ability to understand it, and apply it, without the mental capacity to comprehend it, it remains just a useless piece of information and shows the difference between a wise man and a intellectual, fool.
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Feynman on Scientific Method. - YouTube