Yes, Tononi talks in general terms in that clip, which is part of a much longer interview. The key point he is making here is that consciousness is fundamental to our experience of reality, indeed to all intents and purposes it is our reality. All of our experience is by definition, conscious experience; therefore any attempt to describe, define, or construct a theoretical model of objective reality must begin by giving some account of the consciousness of the observer. Starting with the material world, and arriving at consciousness as an output of that, is putting the cart before the horse. Consciousness has priority, he argues, because the material world is something we access via our conscious minds.
I don't think it is worth trying to take such a top-down perspective of consciousness and figure out what its relationship is to physics. Rather, I would start with simple physical interactions and work my way up. Conscious experience is an interaction between a mind and a physical context. That is, the mind is conscious
of something--its physical environment. An iron filing reacts to a magnetic field, but can it be said to be conscious
of that field or the magnet that generates it? Certainly, they are not conscious of the magnet, but there is a sense in which they directly detect the magnetic field and interact with it. Just like humans detect their environment and interact with it.
Human bodies and iron filings are both physical objects. They both interact with their environment. What is it about physical human bodies that makes them interact differently with their environment than iron filings react with theirs? Both humans and iron filings feel forces of attraction and repulsion, but the human interactions are vastly more complex. We can proceed with such a bottom-up methodology to look at physical interactions between more complex physical objects than magnets and iron filings, but I think at some point it will become clear that the physical fields involving less complex objects are similar to the physical fields involving human behavior, only vastly different in scope. Iron filings obviously don't have brains. They don't build mental models to interpret the sensation of a magnetic attraction, nor do they have associative memories of their interactions. But we can build physical machines--robots--that have some of those more human-like interactions with their physical environments. So we have a means of investigating the relationship between brain activity in human bodies and the reality that those bodies interact with. I wouldn't say that an iron filing has a mind, but I would say that it has some rudimentary component of one.
The ideas Tononi, and philosophers of mind like David Chalmers express, have echoes in quantum theory where the measurement problem, and quantum contextuality, dictate that the observer necessarily interacts with the system she observes, and therefore cannot see the world from a neutral perspective, as it would exist independently of her observation. Similarly in cosmology, Stephen Hawking wrestled with the paradox that the search for the objective 'Archimedean Point' from which to view the universe, is doomed since we are within the universe looking out, rather than laboratory scientists examining an isolated system from the outside.
An interesting property of human thinking is that it can take different perspectives--first person, second person, third person, etc. What can be described from each of those different perspectives is different from descriptions based on the others. So it is wrong to say that one cannot see the world from a neutral or different perspective. One can imagine it from those perspectives. One of the problems with trying to wrestle with these problems as a scientist is that the models one comes up with to describe measured results are somewhat different perspectives on those results, and not all models are useful is solving real world problems. For example, quantum mechanics tells us lots of interesting things about the behavior of a baseball that a pitcher throws, but classical mechanics is a lot more useful in describing it from the perspective of the pitcher. And there is more than one way to interpret fact of the measurement problem, as the physicist Sean M Carroll has been at pains to explain in his popular book
Something Deeply Hidden. You don't need to buy into Everett's MWI model of quantum mechanics to understand his point, but I think he makes it very well. Sometimes scientists get the science right and the metaphors wrong. and scientists have come up with a lot of metaphors while trying to explain the measurement problem.
"Our physical theories don't live rent-free in a platonic heaven. We are not angels, who view the universe from outside. We and our theories are part of the universe we are describing. Our theories are never fully decoupled from us."
- Stephen Hawking, quoted by Thomas Hertog, On the Origin of Time
See what I mean about scientists and metaphors? Why would we want to decouple ourselves from our theories? That doesn't make any sense at all. What we want to do is develop theories that provide us with useful ways to interact with the physical reality that we find ourselves in. Why suffer so much angst over the fact that we will never stop learning new and useful things about that reality?