My guess is this; the two state solution is dead, and the situation will devolve into somewhat resembling Apartheid South Africa.
Given that Democrats and Independents are both trending away from sympathizing with Israel and moving towards sympathizing with the occupied territories, and that they make up 2/3rds of Americans, the possibility of the US flipping back drastically in line with UN positions, or just unilaterally disengaging with Israel, should probably be somewhat concerning to your average Israeli.