Heya
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Signs are absolutely a mean of observation but it is incorrect to call them signs since this presupposes their origin before analysis! In order to treat them scientifically, you would need to determine where an event was or was not a sign of God before referring to it as such.
God's tyre tracks are really all I am looking for.
But lets look at your tyre tracks first. It would be a invalid conclusion to say that a car tyre found in the desert was evidence of human prescence unless you could also draw on other evidence such as, for example, seeing a car or a car tyre being made or used by another human.
Now we all of course have this evidence available to us so it seems trivial to point it out. But it is not trivial to the person who has never seen a car before in his life. If you lived in a state of isolation and happened across this car tyre then it would be an entirely invalid conclusion if you decided that this indicated that somebody else had been there. We actually need much more evidence to reach this conclusion logically and it is only because this evidence is readily available that we miss it.
Unfortunately, in the case of God, this other evidence is not readily available and so we cannot look at something (like an atom) and say it implies a creator. We only know a tyre requires a human because of our knowledge of humans. We can only say an atom is the work of God if we already have knowledge of God.
Anything can be evidence for anything. In order for something to be evidence
for something then it requires an argument of some sort since otherwise we have no reasonable way of moving from the evidence to the conclusion.
It is therefore insufficient to say creation is evidence of God since we need a reason for
why it is evidence for God. Yes
if God created the world, it would indeed be evidence but to assume this, use it to support evidence, and then reach it as a conclusion would be entirely circular.