As a matter of fact, I have.
Nasty emotional stuffs it is.
Of course, I am speaking from the families side, not the side of the one with the injury.
I can only imagine (if that is even possible) how bad it is for the one with the injury.
Certainly. I've seen it, too.
I've never seen someone who claims that an incorporeal soul is the seat of the mind - or even the conscience - ever really reconcile what can happen in the case of a brain injury with their claim.
For those of us who believe that the mind is just "what the brain does," it makes perfect sense that damage to the brain would alter the mind.
For those who claim that the mind - or aspects of it like the conscience - are non-material, the impacts of a brain injury are hard to reconcile. I've seen some use the analogy that injuring someone's brain is analogous to damaging the antenna on a television, but this analogy doesn't work. A damaged antenna gets you static, not a completely different program.
They usually end up arguing that the post-injury person isn't the "real" person or "real soul," despite the fact that the person has thoughts, feelings, a personality, a conscience, etc., thereby conceding that these things can exist without being rooted in a soul.