It seems to me that most defenses of suffering of humans and other species, that is, defenses of the problem of evil or suffering, explicitly hinge on either a) a history which disagrees with consensus scientific opinion (like the earth got corrupted or whatever due to human sin, despite mass extinctions, and hunting and the hunted, occurring before humanity ever existed), or b) some rather un-evidenced proposition that there exists a meaningful afterlife that not only makes up for, but specifically benefits from, suffering in this life. In other words, few would say that this life is all there is, and this life is perfect. The proposition of perfection usually hinges on some unseen promise, and even then, typically does a poor job of taking into account the intricacies of suffering or suboptimal design.