Well, yes, it can be done. But it doesn't support God as such. Rather the metaphysical/ontological status of objective reality in itself is that, it is independent of the mind and that can be known, but what it is otherwise is unknown.
BTW the assumptions of science are methodological naturalism.
In effect all positive claims of what objective reality is as natural or supernatural are both without evidence and/or proof. And at least some theists in effect cheat for the following invalid and unsound deduction.
There is no evidence that objective reality is natural, therefore it is from God.
In a historical sense as for the development from natural philosophy to science as both within philosophy as per epistemology the change was that idea of absolute proof was given up on and the following assumptions were used to secure knowledge:
The universe is real, orderly and knowable.
But these are without evidence or proof, but rather they are the basis for evidence as a method.
The theists gain nothing in support of God by pointing that out, but it is correct none the less that science rests on assumptions about what the universe is.
But in practice for the shared everyday assumption that we are in the universe as such, it means nothing for the practical parts that are objective. It only becomes relevant as in effect how different humans cope with being humans.
It is the demarcation of what is versus what we ought to do, that in the end, is where we get into the fight of what really matters as to how we ought to live our lives. But that is not natural science as such. That belongs to sociology, psychology, philosophy and/or religion.
And there is no unique about that. It is even noted here on a teaching site for what science is and what it can't do.
undsci.berkeley.edu