Apologist William Lane Craig argues the 2nd law of thermodynamics is evidence the universe had an absolute beginning. And whatever begins to exist has a cause. The universe began to exist. Therefore, the universe has a cause. This cause must be non-spatio-temporal and non-material since all that is material had a beginning. Ergo, this cause is how God is described, or as Aquinas liked to say, "This is what people call God."
So, let me explain how it is supposed to be evidence of an absolute beginning.
This is because of the tendency of particles to approach equilibrium in closed systems. As a consequence the universe would evolve to a state of no thermodynamic free energy and would therefore be unable to sustain processes that increase entropy and may no longer be exploited to perform work (since work is obtained from ordered molecular motion). As a result, an infinitely-old universe should therefore have reached equilibrium (i.e., maximum entropy) long ago, but it did not, so the universe began at some finite time in the past.
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In the book "Atheism: The Case Against God", George H. Smith replied as follows:
"Reconciling the Second Law of Thermodynamics with the present state of the universe is not as hopeless as theists like to pretend. To begin with, the Second Law is a statement of statistical probability, and there is nothing inherently contradictory in supposing that a closed system can decrease in entropy or fluctuate between increasing and decreasing entropy states. But this probability, while metaphysically possible, is extremely unlikely, so it is usually ignored in practical applications.
More importantly, however, the Second Law pertains only to closed systems, which, according to many physicists, renders it inapplicable to the universe as a whole. Professor Grunbaum, a physicist, writes:
'An inherent limitation on the applicability of the ... entropy concept to the entire universe lies in the fact that it has no applicability at all to a spatially infinite universe.'
Professor E. A. Milne, commenting on another physicist’s acceptance of the heat-death thesis, writes: 'Jeans’s own studies in the realm of the second law of thermodynamics were all concerned with the kinetic theory of gases, in which the specimen under discussion is supposed walled around in a finite vessel; and to such systems the notion of a heat-death is applicable. But by no means is the same result to be predicted of the whole universe.'
Finally, according to Landau and Evgeny, authors of Statistical Physics: '... in the general theory of relativity the universe as a whole must be regarded not as a closed system, but as one which is in a variable gravitational field. In this case the application of the law of increase of entropy does not imply the necessity of statistical equilibrium.'
Since the concept of entropy can be defined only with reference to closed systems, it cannot legitimately be applied to the universe as a whole. The theist takes a scientific principle derived from a specific context, and attempts to shift this context in order to manufacture a need for god. In the name of science, the theist posits a “god of the gaps,” a god who allegedly fills in the gaps of human knowledge. But gaps of knowledge eventually close, leaving god without a home. The entropy argument is a cosmological argument draped in scientific jargon—but an invalid argument, even when presented in scientific terms, is still invalid."
Smith's rebuttal seems robust to me (although I don't like the way he speaks of theists, i.e., "theists like to pretend". Just because some theists -- viz., apologists -- do it doesn't mean all or most theists do it).
Anyway, I'm eager to hear your thoughts on this.