I actually think the question you are raising is the wise one. The other one, for me, shows a lack of understanding and an understanding I'm very familiar with.
Yes, I think prayer would help in this case, like all cases. It would depend on how the prayer is framed, which goes back to understanding why (and how) this manifested. I do not see Creator God as manifesting anything in the physical that our physical eyes perceive. Yet, I do see same God as allowing it. I think prayer would inevitably help find peace with this. I could see how those words would be perceived as 'that's simple' (as in grossly simplistic), but it would surely mean it wouldn't be framed or filtered through lens of 'only a lazy or cruel jokester' would see this as okay. To me, a medical doctor (not all of them, but many of them) would have that level of peace with it. But that would just be the simplistic version. Another level of peace would fully appreciate the manifestation and if truly something was desired to be done, it would get 'er done.
If that expressed desire is coming from a place of lack (as in 'they, the twins' lack health) and making demands of how the solution needs to occur, I see the (higher) level of peace finding that humorous. And plausibly doing nothing given the 'logic' at work.