The only defense is that they are trying to provoke the argument for better physical explanations.
For instance, vitamin B certainly improves concentration, and alcohol inhibits the mind.
But, of course, it is the mind that decides to consume one or the other.
Essentially it seems impossible to escape dualism, but the problem still persists in:
to what extent the material effects the mind.
To often, people lazily slip into ignoring the physical aspects of consciousness
and dualism often degenerates into solipsistic non-materialism.
Actually the physical still effects consciousness to a far greater extent than any of us can realize.
So the defense is actually methodological:
By assuming a rigid materialist ontology, we stop the mind from degenerating into solipsism.
Shouldn't we just not ignore the physical aspects instead of assuming an unsound position just to make it easier?