One does Not have to feel or looked ' buzzed ' to feel the effects of a drink of wine.
Wine which is No longer wine would have No effect especially on an empty stomach.
If literal blood then some people might think they are drinking their God.
As if their God is an endless supply of blood which could be tapped into like a blood bank.
Wasn't cannibalism the partaking of any blood forbidden according to Leviticus 17:10,14 ?
The blood and body of our Lord exist in quantities sufficient to feed his flock. When, in the Orthodox Divine Liturgy, we pray the prayer known as the epiclesis we believe the bread and wine are changed into the actual body and blood of our Lord by the action of the Holy Spirit (rather than changing their substance while retaining their perceptual attributes at the Words of Institution which is the Roman Catholic belief, although Orthodox sometimes say we believe in transubstantiation for want of a word to properly express this mystical action).
Whereas it would be wrong to drink the blood of a human or an animal for that matter, it is not wrong to drink the blood of our Lord. The bread is of course an easier pill to swallow typologically and easier to distribute without spills, which are viewed by both Catholics and Orthodox as a gross impiety, which is why for some centuries the Roman church denied the chalice to the laity. The Orthodox have always distributed both in both species.
Now, having fasted since the night before, one would expect wine to upset the stomach or have a noticeable effect consumed directly (the Eastern Orthodox put the bread on a spoon with the wine, mixed with boiling water before serving it as this simulates the warmth of real blood; the other Orthodox don't do this), but this is not the case. In contrast the white wine (Orthodox church wine is always red) used in the local Episcopal church upset my stomach every time, even without Eucharistic fasting, and at the same time left that boozey aftertaste of strong wine.
Now what we're discussing is really the mystical theology of the second largest Christian denomination, the Orthodox, and to a large degree, that of the Roman Catholics, who of course retain the top spot for the moment. So while "this is a hard saying" as the masses in John 5-6 said after Jesus stated that to inherit eternal life we must eat his flesh and drink his blood, and indeed most of those present left on that note, happily, the majority of Christians now alive accept that teaching (when one factors in Lutherans who largely accept it and high church Anglicans, the numbers grow a bit more). And it is indeed part of the mystery that with some rare exceptions, for most who partake the texture and taste is pleasant, like bread and wine.
Now all religions worth believing in have a mystical element that defies rational thinking. I find the rationalism of some Protestant denominations to be soul crushing.